For instance, LINC00461 may be an oncogene in CRC by targeting miR-323b-3p through NFIB signaling pathway (Yu et al., 2019), Moreover, lncRNA MIR4435-2HG was reported to play an oncogenic role by promoting CRC growth and metastasis and establish the presence of MIR4435-2HG/miR-206/YAP1 axis in CRC (Dong et al., 2020). Here, YAP1 is linked to colorectal carcinoma.