Several studies have confirmed more common appearance of rs10821936 C allele in hyperdiploid ALL than in ALL with the TCF3-PBX1 or ETV6-RUNX1 fusion genes in either whites or non-white Hispanics (Papaemmanuil et al., 2009; Treviño et al., 2009). Here, TCF3 is linked to acute lymphoblastic leukemia.