NANOG and osteomyelitis: As TWIST1 was the most up-regulated gene in OMRGs of GPL96 platform, NANOG and ERBB2 were closely associated with TWIST1, and they were top 3 core proteins as well in PPI network, we established S. aureus osteomyelitis model, and evaluated the mRNA expression of these three genes in peripheral blood cells and bone of S. aureus-infected mice.