VEGFA and ischemic stroke: Compared to healthy controls (0.61 pg/mL; IQR 0.40–1.01), VEGF-A levels were significantly increased in ischemic stroke patients both <8 h (1.04 pg/mL; IQR 0.80–2.39) (p < 0.05) and at 72 h (5.64 pg/mL; IQR 3.48–8.74) (p < 0.0001), with a significant increase between 8 and 72 h (p < 0.01) (Kruskal–Wallis: chi square = 26.71, p < 0.0001, followed by Dunn's multiple comparison test) (Figure 4B).