CD274 and neoplasm: However, when investigating the surface expression of MHC-I (H-2Db and H-2Kb) and PD-L1, the maternal C1498-luc revealed heterogeneous levels of MHC-I and relatively high level of homogenous PD-L1 expression, and these molecules were upregulated in response to inflammatory stimuli IFNγ that could be considered as inflammatory conditions of tumour sites in vivo (Fig. 3g).