To examine how syntenin-1 affected tumour cell properties in colorectal cancer, we conducted microarray analysis by IPA using SW480 with downregulated syntenin-1, and we found that PTGER2 was suppressed in conjunction with syntenin-1 (Fig. 3c and Supplementary Fig. 2a, b). The gene discussed is SDCBP; the disease is colorectal cancer.