Currently, the most intensively studied TACAs for the development of cancer vaccines are Lewis determinants (Lea, Ley, SLea) and glycans of the Globo class (Gb5, Globo H), which are overexpressed in a range of tumors, as well as carbohydrates present in gangliosides (GM2, GM3, GD2, fucosyl GM1) overexpressed in melanomas, lung, colon, prostate cancer, and mucin‐related TACAs (Tn TF, STn, STF) characterized by their rather simple structures and largely expressed in adenocarcinomas. This evidence concerns the gene TF and cancer.