CRP and type 2 diabetes mellitus: With regard to the anti-inflammatory effect of hydroxychloroquine in T2DM, Amit Gupta [27] has recently shown that diabetic patients with higher baseline levels of high sensitivity C-reactive protein (hs-CRP > 3 mg/l) exhibited a more pronounced, although not significant, improvement in glucose control from baseline to 48 weeks after the initiation of hydroxychloroquine therapy, as compared to patients with lower baseline levels of hs-CRP (≤ 3 mg/l).