So far, we identified eight MYCN target genes ARMC6, DCTPP1, EIF4G1, ELOVL6, FBL, PRMT1, E2F1 and RPS19 which were up-regulated in MYCN amplified neuroblastoma patients and associated with worse prognosis of neuroblastoma in TARGET and GSE85047 datasets. The gene discussed is FBL; the disease is neuroblastoma.