CIB1 and hepatocellular carcinoma: The same pathway, Cip/Kip up-regulation, has been demonstrated in various cancers including, lung cancer (Platta et al., 2007), HCC Hep3B cells (Svechnikova et al., 2007), and human gastric cancer cell lines, OCUM-8 and MKN-74 (Zhang et al., 2006).