PRF1 and neoplasm: They could be classified as (1) tumor growth and metastasis promoting factors containing IFI27, FOXQ1, KRT13, IFI6, and PLAC8 genes, (2) glucose transporter has the SLC2A3 gene, (3) the chemoresistance-associated molecules comprising the DHRS2 and BST2 genes, and (4) the PRF1 and OLFM1 genes with unclear functions.