Moreover, Joypaul et al., (1994) investigated a sample of 260 patients with stomach adenocarcinoma and revealed that p53 was positive in 46% patients (in our study, 41.7% of patients were p53 positive), and similar to the present study, there was no significant relationship between the expression of this marker and grade of tumor, type of tumor (based on the Lauren classification), and lymphatic metastasis; however, a significant relationship existed only between the expression of p53 and the survival rate of patients (with odds ratio = 1.89, 95% confidence interval 1.33-2.69). The gene discussed is TP53; the disease is gastric adenocarcinoma.