A number of studies have reported that there is a significant association between TP53 codon 72 polymorphism and breast cancer risk (Sjalander et al., 1996; Kalemi et al., 2005; Akkiprik et al., 2009; Buyru et al., 2003; Goncalves et al., 2014; Henriquez-Hernandez et al., 2009; Katiyar et al., 2003; Li et al.’ 2002; Baynes et al., 2007) and other studies showed that there is no significant association (Mabrouk et al., 2003; Khadang et al., 2007; Schmidt et al., 2007; Tommiska et al., 2005; Murata et al., 1996). The gene discussed is TP53; the disease is breast cancer.