PCSK9 and coronary artery disorder: For example, PCSK9 mRNA expression in the adrenal gland was associated with an increase in CHD risk: OR 1.09 (95%CI 1.02; 1.16), while PCSK9 expression in the uterus was associated with decreased CHD risk: OR 0.92 (95% 0.88; 0.97).