We also assessed the specificity of degradation of both degraders in several stably-transduced cancer cell lines in addition to H358, namely MIA PaCa2 (pancreas, KRASG12C), A549 (lung, KRASG12S), H1299 (lung, NRASQ61K), HT1080 (fibrosarcoma, NRASQ61K), T24 (bladder, HRASG12V), HCC827 (lung, RASWT but EGFR mutated) and an untransformed cell line: MRC5 (non-transformed lung fibroblast, RASWT). This evidence concerns the gene EGFR and cancer.