Calculation of the SI identified 8/10 and 4/9 (not enough cells were obtained for MP_CD8 stimulation for 1 donor) of the COVID-19 ARDS patients as responders to MP_S and MP_CD8, respectively, whereas 1/10 of the HC responded to the MP_S stimulation (Fig. 4B, C and 7). This evidence concerns the gene CD8A and acute respiratory distress syndrome.