FEZF1 and neoplasm: The results indicated that plasma FEZF1-AS1 expression was significantly upregulated in patient groups with positive distant metastasis (P < .0001; Fig. 3A), positive lymph node metastasis (P < .0001; Fig. 3B), advanced clinical stage (P < .0001; Fig. 3C), and larger tumor size (P < .0001; Fig. 3D) compared to the control groups.