DRD4 and obesity due to melanocortin 4 receptor deficiency: Therefore, the aim of this study was to use a novel genomic approach that imputes the gene expression of DRD4 in prefrontal cortex using individual level genomic information[21] to evaluate how genetically-influenced prefrontal brain dopamine function interacts with environmental obesity risk (captured by SES) to influence indices of behavioral (multi-item ad libitum meal intake) and neurobehavioral (food go no go task performance) obesity risk in adolescents.