SNCA and Parkinson disease: The frontal regions are always correlated with pathological alpha‐synuclein accumulation (Compta et al., 2015; Guo et al., 2018), a core pathology of PD (Braak et al., 2003) and have also been associated with motor disturbances in PD (Guo et al., 2015), which indicates that the frontal area is a target of pathological changes in PD.