Relevant researches show that osteosarcoma cells have enhanced proliferation and migration ability after co‐culture with MSCs in vitro153; MSCs enhance the thermal resistance of ovarian cancer cells through CXCL12‐dependent pathways and promote tumour development and angiogenesis in mice with colon cancer154, 155; With support from MSCs, breast cancer cells acquire high metastasis ability through the CCL5/CCR5 feedback axis.156, 157. This evidence concerns the gene CXCL12 and neoplasm.