Data showed that there was almost no CXCL8 secretion with fewer BMSCs (CD105‐positive cells) in the normal oral epithelial cells, and there were a little more CXCL8 secretion and BMSCs around blood vessels (co‐localization shown in orange colour) in the epithelial dysplasia (Figure 1C). This evidence concerns the gene ENG and intraepithelial neoplasia.