By Pearson correlation analysis, the expression of FBXW7 was found to be negatively correlated with miR-223-3p expression, but remarkably positively correlated to the expression of RASA1 in renal cancer tissues, indicating that RASA1 might up-regulate FBXW7 expression by down-regulating miR-223-3p expression (Figure 6K,L). This evidence concerns the gene FBXW7 and renal carcinoma.