In particular, we found that maspin overexpression is correlated with better prognosis for the MSI subtype in early stage cancers (maspin-high mean OS of 110.9 months vs. maspin-low mean OS of 73.9 months), but not in the early stage MSS subtype (maspin-high mean OS of 70.7 months vs. maspin-low mean OS of 81.0 months) or late stage colorectal cancers. The gene discussed is SERPINB5; the disease is colorectal cancer.