In line with these findings regarding a pro-proliferative function of AATF in solid tumors (17), Folgiero et al. (54) described a similar effect of AATF in B-cell precursor acute lymphoblastic leukemia (BCP-ALL), where c-Myc driven AATF signaling promoted lymphoblast proliferation and ALL progression. This evidence concerns the gene MYC and acute lymphoblastic leukemia.