GSEA was carried out to examine the biological effects of the as-constructed lncRNA model, and our results suggested that the high score of lncRNA model showed significant enrichment in pathways including, bladder cancer, basal cell carcinoma, non-small cell lung cancer, nicotinamide and nicotinate metabolism, the notch signal transduction pathway, the p53 signal transduction pathway, thyroid cancer, pancreatic cancer, the VEGF signal transduction pathway, and the Wnt signal transduction pathway (Figure 8). This evidence concerns the gene VEGFA and thyroid cancer.