Sin et al.47 also analyzed the role of SFTPC in stem cells in lung AC, and they found cancer stem cells in 52 out 57 samples; additionally, those with a bronchioalveolar phenotype SFTPC (+) were more differentiated and patients had a better prognosis compared to stem cells, which were related to a poorer prognosis. The gene discussed is SFTPC; the disease is cancer.