However, the log-rank test demonstrated that the 5-year overall survival (OS) for patients with low HSP47 expression in tumor tissues was significantly higher than that in the high-HSP47 group in both the TCGA [hazard ratio (HR) = 0.50 (95% confidence interval, CI 0.33–0.76), P = 0.002] (Figure 1D) and curated CRC Data cohorts [HR = 2.91 (95% CI 1.92–4.41), P < 0.001] (Figure 1E). Here, SERPINH1 is linked to neoplasm.