In a study using different MDR variants, KG1a and K562 leukemia cells (P-gp overexpressing vs. parent cells) and P-gp inhibitors (SDZ PSC 833, SDZ 280-466, and LY335979), it was shown that the inhibition of P-gp caused the failure of cytokinesis and apoptosis119. This evidence concerns the gene PGP and leukemia.