ACTA1 and renal fibrosis: Our results revealed that the elevated expression of fibronectin and α-SMA induced by ectopic expression of miR-155-5p in NRK-49F cells was effectively eliminated by loss function of STAT3 (Figures 4(e) and 4(f)), suggesting that miR-155-5p is involved in renal fibrosis via regulating the phosphorylation of STAT3.