KCNH2 and cancer: One of the K+ channels most often dysregulated in cancer is KV11.1 (or hERG1), which regulates the resting Vm in excitable cells (Bauer and Schwarz, 2018), as well as in cancers arising from excitable (e.g. neuroblastomas, Crociani et al., 2003) and non-excitable tissues.