We observed that β1-integrin co-immunoprecipitated with both KV11.1 and NHE1 in CRC cells before cell seeding (“pre seeding” in Figure 4), indicating the formation of a β1/Kv11.1/NHE1 complex, whose assembly was further promoted by cell adhesion onto Col-I for 90 min (lanes 3 and 4 in Figure 4). The gene discussed is SLC9A1; the disease is colorectal carcinoma.