(a) CD14+ cells isolated from patients with hepatocellular carcinoma (HCC) were classified into four subgroups (PD–L1+PD–L2+ CD14+ cells, PD–L1+PD–L2− CD14+ cells, PD–L1−PD–L2+ CD14+ cells and PD–L1−PD–L2− CD14+ cells). The gene discussed is PDCD1LG2; the disease is hepatocellular carcinoma.