TIA1 and anaplastic large cell lymphoma: Expression of cytotoxic molecules TIA-1 and granzyme B was observed in all MAX-negative ALCL patients, but only 55% (12 of 22 patients) and 48% (10 of 21 patients) of MAX-positive ALCL patients, respectively (p = 0.013, p = 0.017, respectively) (see Supplementary Figure S2A online).