MAX and anaplastic large cell lymphoma: In summary, we demonstrated that (1) decreased MAX expression could be a poor prognostic factor in ALCL, probably through cytotoxic molecules in coordination with MYC, (2) decreased MAX expression is related to histological non-common patterns of ALCL (e.g., patients that had a poor prognosis), and (3) decreased MAX expression might help to distinguish between ALCL and PTCL-NOS.