In the VdH cohort, MMP-2 levels were associated with age (0.95; 95% CI 0.27 to 1.63, p = 0.007), mRS 90 days (3.8; 95% CI 0.48 to7.07, p = 0.025), hypertension and 90-days mortality (OR = 1.032, 95% CI 1.002 to 1.064, p = 0.039 and OR = 1.025, 95% CI 1.003 to 1.048, p = 0.027, respectively). This evidence concerns the gene MMP2 and hypertensive disorder.