To date, many RET fusions have been reported in NSCLC, including KIF5B–RET, CCDC6–RET, NCOA4–RET, TRIM33–RET, RUFY2–RET, CUX–RET, KIAA1468–RET, CLIP1–RET, ERC1–RET, MYO5C–RET, EPHA5–RET, PICALM–RET, FRMD4A–RET, KIF13A–RET and WAC–RET17. The gene discussed is PICALM; the disease is non-small cell lung carcinoma.