YAP1 and small cell lung carcinoma: Further examination of SCLC lineage drivers [2, 3] showed that methylation of the probe cg20782778 in the body of YAP1 (encoding yes-associated protein 1 which regulates the Hippo pathway [2, 65]) was associated with resistance to the mTOR inhibitor rapamycin; ρ = 0.4904, pO= 2.91 × 10−5, pFDR = 0.1282; Supplementary Tables 6 and 7.