Three AHAs (AHA3, AHA5, AHA8) were selected by univariate analysis, and then AHA3 (IgG anti-IgG4 F(ab’)2pepsin) and AHA 5 (IgA anti-IgG1 F(ab’)2pepsin) were selected as independent variables for RA diagnosis by multivariate logistic regression analysis as shown in Table 3. This evidence concerns the gene CD79A and rheumatoid arthritis.