uPA has been reported to be overexpressed in several type of cancers, such as esophageal [156], gastric [71], colorectal [159], pancreatic [119], breast [40, 96, 162], cervical [82], ovarian [90], prostate [134], leukemia [148], brain [64] and renal cancers [168]. The gene discussed is PLAU; the disease is cancer.