INS and Insulin resistance: Insulin level was decreased from 19.35 ± 0.304 to 8.80 ± 0.181 mIU/L, p < 0.001, and the Homeostatic Model Assessment-Insulin resistance (HOMA-IR) index was reduced from 6.48 + 0.164 to 2.52 ± 0.061, p < 0.001, Table 2).