In addition, we found that the expression of Cidea in the liver was upregulated by the high-fat diet, and antibiotic use reduced its expression, and this might result in less hepatic lipid droplet formation and storage because the highly expressed Cidea in the liver of mice is associated with hepatic steatosis under the high-fat diet feeding [39, 40]. The gene discussed is CIDEA; the disease is Hepatic steatosis.