It was used to determine apoptosis induction in cells by alvaxanthone and rheediaxanthone B. In each of the three cell lines, compared to the respective non-treated control, treatment with each of the two compounds for 48 h led to a significant activation of the caspases 3/7 (by 2- to 10-fold for alvaxanthone and 8- to 18-fold for rheediaxanthone B), the effect being stronger in cancer than normal cells (Figure 4). Here, CASP3 is linked to cancer.