Moreover, the identification of a differential expression of IL-1β, IL-4 and IL-8 in relation to the different forms of laminopathy might provide a new hint for the understanding of the pathogenic mechanisms underlying the diverse phenotypes caused by LMNA mutations, while specific analysis of the secretome of HGPS, MADA and FPLD2 will identify relevant pathogenetic pathways for those diseases. This evidence concerns the gene CXCL8 and laminopathy.