GHRL and type 2 diabetes mellitus: Moreover, the involvement of this specific pathway in diet-induced chronic diseases, like obesity, type 2 diabetes mellitus (T2DM) and metabolic syndrome, has also been highlighted [38] and is also related to the presence of dysfunctional visceral adipose tissue with altered adipokine and ghrelin patterns, resulting in turn with greater ASCVD risk [8,39,40,41,42].