KL and neoplasm: Cell lines A2780, SKOV-3, OVCA 432, OVCAR-5, OVCAR-8, CaOV3, CaOV4 [51]C57BL/6 mice xenografts using A2780 cells [51]Decreased Klotho expression in invasive disease [51]Klotho high expressing tumours associated with improved survival [51]