CHD4 and lip and oral cavity carcinoma: The nucleosome remodeling deacetylase complex (NuRD), also known as Mi-2, according to stoichiometry data [114,115], is composed of one copy of the CHD3 (Mi2α) or CHD4 (Mi2β) proteins (chromodomain, helicase, DNA binding domain), one HDAC1 or HDAC2, three MTA1/2/3 (metastasis associated), one copy of MBD2 and MDB3 proteins (Methylated CpGBinding), six copies of RbAp46/48 proteins (retinoblastoma associated protein), two GATAD2a/b (p66a/b) and two DOC-1 (deleted in oral cancer) [115].