Based on this test, in five of the ten proteins individually analyzed, i.e., APOA1, C3, a1AT, APOL1, and FCN3, no significant differences were observed among the glaucoma sample groups (DBA/2J_G4 vs. DBA/2J_G10 and DBA/2J_G14, i.e., preglaucomatous mice at 4 months and glaucomatous mice at 10 and 14 months old). The gene discussed is APOL1; the disease is glaucoma.