CDKN1A and neoplasm: The pathways induced by these stimuli finally converge in a set of senescence genes, the best known of which are the tumor suppressors Cdkn2a-p16, Cdkn2a-p19, Cdkn1b-p27, Cdkn2b-p15 or Cdkn1a-p21, resulting in proliferative arrest [9, 10].