To identify and characterize novel factors potentially related to TGF‐β‐induced tumour aggression in oesophageal cancer, we treated human oesophageal cancer cell line Eca109 with TGF‐β and then used microarray analysis to compare RNA expression levels between TGF‐β‐treated and untreated cells, observed TGF‐β‐dependent up‐regulation of FAM83H‐AS1 (FAM83H antisense RNA1, also known as onco‐lncRNA‐3). Here, SACK1H is linked to neoplasm.