To investigative the expression of METTL3, METTL14, WTAP, ALKBH5, FTO, and YTHDF2 in patients with SLE and HC, PBMCs from 28 SLE patients and 26 age‐ and sex‐matched HC were collected to detect their expression using qRT‐PCR. The gene discussed is FTO; the disease is systemic lupus erythematosus.