As shown in Figure 1, the expression of METTL14, ALKBH5, and YTHDF2 in PBMCs from SLE patients were significantly decreased than that in HC (all p < .050), while the expression of METTL3, WTAP, and FTO in PBMCs from SLE patients and HC was unchanged (all p > .050). This evidence concerns the gene YTHDF2 and systemic lupus erythematosus.