The present study was designed to determine the expression of p63, mammary serine protease inhibitor (maspin) and matrix metalloproteinase2 (MMP-2) in mucoepidermoid carcinoma (MEC) and adenoid cystic carcinoma (ADCC) of salivary glands due to various cellular differentiationand structure. This evidence concerns the gene SERPINB5 and adenoid cystic carcinoma.