IAPP and chronic myelogenous leukemia, BCR-ABL1 positive: Using synthetic peptides and a combination of spectroscopic and biophysical techniques, we demonstrated that MGO glycation of IAPP results in the formation at Lys1 of CML or CEL, two of the most common AGE products (Fu et al., 1996; Frye et al., 1998; Xue et al., 2011).